Anna Prins scored a career-high 32 points and Iowa State advanced to its first Big 12 tournament championship game in six years, beating Oklahoma 79-60 on Sunday.
Chelsea Poppens, the other Iowa State senior starter, had 14 points and 10 rebounds.
The Cyclones (23-7) trailed only once. After Joanna McFarland's 3-pointer put Oklahoma up 10-7 less than 4 minutes into the game, Brynn Williamson's 3-pointer opened a 17-0 run when five different Iowa State players scored.
McFarland and Morgan Hook had 12 points each for Oklahoma (22-10), which overcome a 22-point second-half deficit Saturday to beat West Virginia.
Iowa State, which kept a double-digit lead after that 6-minute spurt, plays No. 1 Baylor (31-1) on Monday night.
The Cyclones were tournament champs in 2000 and 2001, and lost their last title game appearance to Oklahoma in 2007.